O'Farrell said his weight loss with the drug was "almost instant" and that, as well as losing more than five stone (34kg) so far, he has more energy and has been able to exercise for the first time in years.
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CRISPR–Cas9 screening identifies CLCC1 as a factor that increases neutral lipid flux to prevent hepatic steatosis and promotes nuclear pore complex assembly by promoting membrane bending and fusion.
In September 2025, she launched a business offering support to others in Guernsey because of her experience.